Abdominal pain is more common in clinical practice, many diseases can cause continuous abdominal pain, the most common causes are the following: i. Acute cholecystitis, manifested as continuous abdominal pain in the right upper abdomen, and often accompanied by paroxysmal aggravation, patients will have abdominal distension, nausea, vomiting, and even fever, it is recommended that patients improve the ultrasound of gallbladder and routine blood tests. Second, acute appendicitis, manifesting as continuous pain in the right lower abdomen, often accompanied by fever, some patients will have nausea, vomiting, and pressure pain at the point of McDonald’s. Patients are recommended to improve blood routine, appendix ultrasound or CT examination. Intestinal obstruction, manifested as continuous colic around the umbilicus, often accompanied by abdominal distension, nausea, vomiting, anal cessation of exhaustion and defecation. Fourth, perforation of the gastrointestinal tract, such as patients with gastric perforation or duodenal perforation can lead to persistent upper and middle abdominal distension and pain. So many diseases can cause persistent abdominal pain, it is recommended that patients go to the hospital for detailed examination to clarify what kind of disease and then carry out the corresponding treatment.