Clinical manifestations of drug-induced renal damage can be oliguria, anuria, hematuria, proteinuria, hypoproteinemia, hypertension, edema, fever, drug rash and so on. Drug-induced renal damage refers to taking drugs that cause damage to the kidneys. If patients use aminoglycosides (e.g. gentamicin), it may cause acute renal failure, and patients will have oliguria, anuria, hematuria, edema, hypertension and other manifestations. If patients take non-steroidal anti-inflammatory drugs (e.g., ibuprofen) may lead to nephrotic syndrome, which may be characterized by proteinuria, high degree of edema, and hypoproteinemia. In addition, if patients use penicillin (amoxicillin capsule), cephalosporin (cefazolin) antibiotics, then it may lead to renal tubulo-interstitial disease, and patients may have symptoms such as hematuria, proteinuria, fever, and drug rash. It is recommended that patients taking drugs after the occurrence of kidney damage, the need for timely regular hospital medical treatment, under the guidance of the doctor for the severity of kidney damage, choose the appropriate measures for treatment.