A throwaway term, “celiac disease.”

“Celiac disease, a common clinical term, has always been the target of gynecologists who have been actively examining, diagnosing and even treating the disease in the hope of curing and preventing cervical cancer, and has caused anxiety among millions of women around the world. It is important to have a deep understanding of how celiac disease should be viewed and why this term has disappeared from the latest edition of Obstetrics and Gynecology. Traditional meaning of celiac disease: The reddish, fine granular appearance of the vaginal part of the cervix at the ectocervix is called celiac disease. The surface of the erosion is covered by a single layer of columnar epithelium of the intact cervical canal, and the mesenchyme underneath is reddish due to the thinness of the columnar epithelium. Obstetrics and Gynecology, Fifth Edition (2000) describes: Cervical erosion is a common pathologic change in chronic cervicitis. The appearance of the vaginal part of the cervix at the external opening of the cervix is a fine granular red area called cervical erosion. The boundary of the erosion surface is well demarcated from the normal cervical epithelium. The surface of the erosion is covered by the intact columnar epithelium of the cervical canal, due to the poor resistance of the columnar epithelium of the cervical canal, pathogens are prone to invade and inflammation occurs. Cervical erosion can be divided into Ⅰ degree, Ⅱ degree, Ⅲ degree. Obstetrics and Gynecology, Sixth Edition (2004) describes: Cervical erosion is one of the most common pathologic changes in chronic cervicitis. The appearance of the vaginal part of the cervix at the external opening of the cervix is a finely granular red area called cervical erosion. The surface of the erosion is covered by intact columnar epithelium of the cervical canal, which is not true erosion because the columnar epithelium is thin and the mesenchyme underneath it transmits red color. The pathology of true celiac disease refers to epithelial detachment and ulceration. Foreign countries have abandoned the term cervical erosion, renamed cervical columnar epithelial ectasia, because of China’s application of cervical erosion for many years, this book still follows the term. Obstetrics and gynecology seventh edition (2008) describes: after puberty, in the role of estrogen cervical development and enlargement, the cervical tube mucosal tissue outward, that is, the cervical tube columnar epithelium and its mesenchymal components under the cervical vaginal part of the cervical tube, so that the original squamous-columnar intersection outward, the original squamous-columnar intersection part of the medial side of the cervical tube covered with a single layer of columnar epithelium is thin, and the mesenchyme under the transmittance of the red color, the appearance of a fine granular red zone, the appearance of the red zone. The appearance of a fine granular red area is called columnar epithelial ectasia. Because it looks like erosion to the naked eye, it used to be called “cervical erosion”, but in fact it is not true erosion. After menopause, estrogen levels drop, the cervix atrophies, and the original squamous-columnar junction returns to the cervical canal, making the cervix smooth. The term “celiac disease” is a thing of the past, replaced by the term “columnar epithelial ectasia”. Recognize the following terms: Columnar epithelial ectasia: Exposure of the single layer of columnar epithelium of the cervix to the vaginal part of the cervix. It is a physiologic change that reflects estrogen levels in the body. Cervical ectropion: The lining of the cervical canal protrudes outward toward the external cervical opening and is seen as a longitudinal fold. It can be congenital or due to injury, and is often seen in the cervix after childbirth. Eccrine erosion: epithelial detachment and ulceration. Can be caused by chemical injury; true erosion is rare. Cervical transformation zone: the area of the cervix where the columnar epithelium is replaced by pyogenic squamous epithelium of varying degrees of maturity is called the transformation zone. This is the area between the new squamous columnar junction and the original squamous columnar junction. Also called the zone of migration. Acute cervicitis: microscopically, vascular congestion is seen, the mucosa and submucosal tissues, a large number of neutrophils infiltrate around the glands, and purulent secretion is seen in the glandular cavity, which requires treatment. Chronic cervicitis: microscopically, the mucosa and submucosal tissues are seen to be infiltrated with a moderate amount of lymphocytes, and squamous metaplasia may occur in the overlying epithelium, which has no obvious clinical significance. How to look at the cervical columnar epithelial ectasia 1, to establish a concept, “cervical erosion” did not occur epithelial erosion, the epithelium is intact, just covered with columnar epithelium, in the life of a woman, due to changes in estrogen levels, the squamous column intersections will be dislocated. Normal physiological state do not much interference. As the term “celiac disease” has been used for many years, so that some doctors are difficult to change the name, should be gradually abandoned. 2, ectopic columnar epithelium squamous metaplasia after the formation of the transformation zone, the transformation zone can be large or small. When cervical cancer cell screening (TCT) found suspicious, colposcopy to identify normal and abnormal transformation zone is very important. Normal transformation zone minimizes excessive treatment. 3, the necessary conditions for intervention: ① obvious clinical symptoms; ② exclude malignant lesions, such as through TCT screening, HPV-DNA testing, colposcopy, of which TCT is the first step of China’s current screening cervical cancer maneuver, to confirm that there is no possibility of malignant lesions before the intervention, the intervention of physical therapy is appropriate; ③ treatment of specific pathogens infections; ④ informed consent of the patient. With the development of medical science, we have a new understanding of cervical columnar epithelial ectasia. However, due to the exaggerated claims of cervical columnar epithelial ectasia by some doctors, it causes fearfulness of patients, repeated treatment and over-treatment, which is not desirable.