Renal osteodystrophy is a collective term for the skeletal changes that occur after the development of chronic renal insufficiency. It mainly refers to the symptoms of renal osteodystrophy. Chronic renal failure, the end stage will enter the state of uremia, patients will be on hemodialysis for a long time, this situation is easy to cause fibrous osteitis, osteoporosis, renal osteosclerosis and renal osteochondrosis, etc.. All of these conditions are manifestations of renal osteodystrophy. These uremic patients with osteodystrophy can suffer from bone pain, difficulty walking, and even prolonged spontaneous fractures, which can aggravate the condition. Renal osteodystrophy is mainly caused by vitamin D3 deficiency, secondary hyperparathyroidism, malnutrition, aluminum toxicity and iron overload. The early diagnosis of this disease requires bone biopsy, and general bone x-rays can reveal more serious abnormalities. The treatment for renal bone disease is mainly directed at the primary disease, maintaining the stability of blood calcium and parathyroid function, preventing fractures, and in the case of a more stable primary disease, this osteodystrophy, the prognosis is relatively better.