Fever with cough, sputum and chest pain is one of the symptoms of respiratory diseases. Respiratory diseases are acute and chronic inflammatory diseases of the respiratory tract such as colds, bronchitis, bronchiectasis, and pneumonia, which are common and more dangerous. Respiratory diseases are caused by a variety of viral infections. So, how to differentially diagnose fever with cough, sputum and chest pain? The following is the differential diagnosis of fever with cough, sputum and chest pain: 1. Fever with hemorrhage is common in severe infections and blood diseases. The former, such as severe measles, epidemic hemorrhagic fever, dengue fever, viral hepatitis, typhus, septicemia, infective endocarditis, leptospirosis. The latter, such as acute leukemia, acute aplastic anemia, malignant histiocytosis. 2. Fever with enlarged lymph nodes and tenderness may be due to local infection. If the whole body lymph nodes are swollen, it suggests that there may be lymph node tuberculosis, leukemia, lymphoma, metastatic cancer, etc. 3. Fever with joint swelling and pain may be due to sepsis, scarlet fever, brucellosis, tuberculosis, rheumatic fever, connective tissue disease, gout, etc. 4. Fever with rash Commonly seen in rash infectious diseases. For example, measles, scarlet fever, etc. 5.Fever accompanied by abdominal pain, diarrhea, nausea, vomiting Commonly found in digestive system disorders. 6, fever with frequent urination, urinary urgency, painful urination, back pain common in urinary tract infection As mentioned above, there are many causes of fever, both physiological and pathological, patients should not misunderstand that fever is caused by infection and abuse antibiotics and antipyretics. As with other systemic diseases, a thorough and detailed history and physical examination are the basis for the diagnosis of respiratory diseases, and X-ray chest examination is particularly important for pulmonary lesions. Since respiratory diseases are often a manifestation of systemic diseases, they should also be combined with the results of routine laboratory tests and other special examinations to make a comprehensive and integrated analysis and try to make a diagnosis of etiology, anatomy, pathology and function.