Large pores on the face with pimples and blackheads are mostly caused by the vigorous secretion of sebaceous glands on the face, and the oil cannot be discharged normally in the pores and accumulates in the pores or oxidation occurs. The problem of large pores on the face with pimples and blackheads can be improved through skin cleansing, topical medication, oral medication and photoelectric therapy under the guidance of a doctor: 1. Skin cleansing: attention should be paid to the maintenance of the skin, mild and non-stimulating cleansing products can be used, cleansing 2-3 times a day is appropriate, too many times cleansing may promote the secretion of sebaceous glands and aggravate the symptoms of large pores, pimples and blackheads, it is also necessary to Pay attention to skin moisturizing and sun protection to reduce the stimulation of external factors on the skin; 2. Topical medications: topical retinoic acid, salicylic acid, and retinoic acid cream can be used topically for exfoliation treatment, which has a certain anti-inflammatory effect and helps dissolve blackheads and pimples, peel off the aging keratin layer, and promote the renewal of keratinocytes and the proliferation of elastic fibers in the dermis. If accompanied by inflammation and symptoms such as local abscesses, topical clindamycin phosphate gel and ketoconazole cream are also needed for relief; 3, oral medication: experimental studies have shown that oral isotretinoin and other drugs can improve the symptoms of enlarged pores, acne and blackheads to a certain extent, and when topical medication cannot relieve them, they can be treated by oral medication; if accompanied by inflammation, anti-inflammatory drugs such as cefuroxime can also be taken to improve 4, photoelectric treatment: such as strong pulse light, laser, etc., to help promote collagen production, improve skin quality, reduce pores, improve the situation of large pores, acne and blackheads on the face; 5, drug injection: Botox injection, hydrophobic injection to reduce facial oil secretion, promote the new collagen, when the symptoms are serious can also be used in combination with Botox and hydrophobic injection. In addition, avoid staying up late in daily life, keep your mood relaxed, eat more fresh vegetables, fruits and vitamin-rich foods, and eat less spicy and oily stimulating foods, which can effectively promote skin quality improvement.