In 1994, WHO proposed to abandon the concept of “menopause” and recommended the term “perimenopause”. Perimenopause refers to the period from the onset of endocrine, biological and clinical features associated with menopause until within one year of menopause. Two-thirds of women experience a range of symptoms caused by the decline in ovarian function and reduction in sex hormones, called perimenopausal syndrome. During the first half of menopause, about half of women experience menstrual disorders, irregular menstrual cycles, long duration and increased menstrual volume. Although fertility is low and there is a possibility of unwanted pregnancy, attention should still be paid to contraception, and for those with abnormal bleeding, they should be alerted to the occurrence of endometrial cancer. The most common symptoms of perimenopause are hot flashes, bouts of redness of the skin on the face and neck, accompanied by baking heat, followed by sweating. There are also mental and neurological symptoms, such as agitation and irritability, anxiety and depression. Some women experience urinary and genital tract symptoms, urinary incontinence, recurrent vaginitis, inflammation of the urinary tract, and vaginal dryness. In addition skin wrinkles increase, thinning, dryness, itching, hyperpigmentation, and mild hair loss. Postmenopausal women are also prone to atherosclerosis, myocardial ischemia, infarction, hypertension, stroke and other cardiovascular diseases and osteoporosis. During the perimenopausal period, women experience varying degrees of endocrine, somatic and psychological changes.