Diabetic nephropathy in early stage will appear high glomerular filtration rate, clinical symptoms, microvascular changes and other symptoms. 1. High glomerular filtration rate: high glomerular filtration rate occurs after the total amount of blood passing through the glomerulus and the amount of glomerular urine are formed, so high glomerular filtration rate will appear in the early stage of diabetic nephropathy. 2. Clinical symptoms: the main clinical symptoms of diabetic nephropathy in the early stage are pale, lack of energy, foamy urine, increased urinary output, which will cause metabolic disorders, and once it develops into end-stage nephropathy, it will be more difficult to treat. 3. Microvascular changes: early diabetic nephropathy will appear blurred vision, check the fundus of the retina, will find microvascular changes in small blood vessel damage. It is recommended that patients go to the hospital for examination, and the doctor will give diagnosis according to clinical symptoms, and timely compliance with the doctor’s instructions for treatment.