Antipyretic suppositories are antipyretic drugs administered through the anus and absorbed by the rectal mucosa, and can play an obvious antipyretic effect in adults about half an hour after use, which is a good effect, small side effects, fast absorption, and a more commonly used clinical antipyretic method. Generally, for adults with fever below 38.5℃, the first choice should be physical cooling, such as applying antipyretic patches or warm water wipes to cool the body. If the body temperature rises above 38.5℃, you can consider applying antipyretic suppositories or taking oral antipyretic and analgesic drugs. Among them, antipyretic suppositories are easy to use, stuffed into the anus, less irritating to the mucous membrane, safer and conducive to reducing fever. If, after applying antipyretic suppositories and auxiliary physical fever reduction, the patient’s body temperature still does not drop and the fever is high for more than two consecutive days, it is recommended to promptly go to the hospital for routine blood tests to understand what causes the fever and take corresponding treatment measures according to the test results, and not to blindly use drugs on your own to avoid delaying the best time for treatment. In addition to giving fever-reducing treatment, patients should pay attention to the following matters during fever, which can assist in relieving the condition: 1. According to the fever temperature, increase or decrease clothing in a timely manner to maintain a balance between heat production and heat dissipation; 2. Patients with reduced appetite during fever should ensure a light diet, balanced nutrition, avoid spicy and stimulating foods, eat more foods rich in vitamin C, and drink more water; 3. and maintain indoor air humidity.