Patients with diabetes can do IVF if their blood sugar is well controlled. It is important to keep glycosylated hemoglobin below 7.0% and blood glucose under control before IVF, and not to have excessive high blood glucose or low blood glucose, otherwise conception is not possible.
In addition, diabetic patients should have fundus tests and kidney function tests before IVF. If the patient already has diabetic nephropathy or diabetic retinopathy, conception may exacerbate the complications. For these patients it is important to weigh the pros and cons to decide whether to have a child. Regular monitoring of renal function and urine microalbumin, and regular funduscopic examinations should also be performed during pregnancy. Also blood glucose control should be stricter after conception, with pre-meal and fasting blood glucose between 3.3-5.6 mmol/L and peak postprandial blood glucose between 5.6-7.1 mmol/L, and try to avoid hypoglycemia.
Diabetic patients undergoing in vitro fertilization can use human insulin or partial insulin analogs for glucose lowering throughout to reduce the risk of maternal complications and congenital anomalies in the fetus and newborn.