Ulcerative colitis is an intestinal disease of unknown etiology, mainly involving the rectum and sigmoid colon, but can also affect the entire colon and terminal ileum. The clinical manifestations are mainly diarrhea, mucopurulent stools, abdominal pain or urgency; some cases have fever, weight loss, anemia and other systemic symptoms. A few cases are associated with extraintestinal diseases such as arthritis, spondylitis, erythema nodosum, cardiomyopathy, oral ulcers, and iridocyclitis. Newer studies of extraintestinal manifestations have focused on benign increased intracranial pressure and cardiovascular pathologies, including aortitis and endocarditis. Chronic colitis belongs to the categories of dysentery, diarrhea, intestinal wind, and dirty poison in Chinese medicine, and is believed to be caused by spleen deficiency, external evil, poor diet, emotional disorders, and internal injuries due to fatigue. The disease is located in the large intestine but is closely related to the spleen, liver and kidneys. At the beginning of the disease, the disease is mostly internalized by dampness and heat, but after a long period of time, the disease is associated with kidney and liver deficiency. The new treatment of oral Chinese medicine and “enteritis clear enema” enema local drug delivery has improved the cure rate of ulcerative colitis, delayed recurrence and achieved good results, which is welcomed by the majority of patients. “Enteritis Qing enema” has the function of strengthening the spleen, relieving dampness, clearing heat and detoxification, relieving spasm and pain, clearing the intestine and stopping bleeding, protecting intestinal cells from damage by pathogens, blocking other inflammatory reactions, rapidly reducing the clinical symptoms of chronic inflammation of the colon, accelerating the repair of intestinal mucosa, restoring and maintaining the physiological function of the mucosal barrier. ”Enteritis Clear enema” reaches the colonic lesion and is absorbed through the portal venous system, inferior vena cava system and rectal lymphatic system, thus quickly increasing the concentration of the drug and the concentration of the blood drug in the lesion, improving local blood transport, protecting the ulcer surface of the intestine, quickly promoting the absorption of inflammation and healing of the ulcer, and avoiding or reducing the effect of digestive juices and digestive enzymes on the drug. It can also avoid or reduce the influence and damage of digestive fluid and digestive enzymes on the action of drugs, which is conducive to the effect of drugs. The treatment of ulcerative colitis by TCM has remarkable efficacy and shows a broad prospect. The treatment is based on the identification of evidence, and Chinese medicine is divided into types to treat the root cause and improve the collective immune function and resistance to disease. Chinese medicine retains enema to treat the symptoms and drive away the evil in order to achieve both the symptoms and the root cause, thus promoting the cure of ulcerative colitis and improving the efficacy.