Severe toothaches are mostly caused by acute pulpitis attacks, which are unbearably painful and should be treated promptly. However, many patients do not understand and ask: Is it okay to take medicine for pulpitis? Why do we have to kill the nerve? Pulpitis is not effective because the medication does not reach the pulp cavity and the inflammation is not effectively relieved, so the nerve must be killed for treatment. The pulp tissue is located in the pulp cavity, and the pulp is connected to the rest of the body through the narrow apical foramen. In addition to the apical foramen, the pulp is surrounded by the hard dentin wall, so it is not easy to establish drainage when inflammation occurs, so that inflammatory exudate accumulates, and the lack of elasticity of the dentin wall limits the expansion of the inflammatory tissue, and the pressure in the pulp cavity increases, so the infection spreads easily to the whole pulp, and the increased pressure in the pulp cavity compresses the nerve and produces Once the pulp cavity is penetrated, the pressure drops and the pain decreases abruptly. Therefore, in most cases of pulpitis, the first step of the dentist is to help the patient open the pulp to reduce the pressure in the pulp chamber, which is the first step of root canal treatment – opening the pulp. Pulpitis causes tooth pain that occurs at night and is so severe that you cannot sleep. Many patients feel fine when the tooth does not hurt after the pulp is opened to kill the nerve, and do not insist on finishing the root canal treatment.