What is necrotizing fasciitis? ”Flesh-eating bacteria invade the fascia (connective tissue between muscle and muscle and between muscle and skin) and spread along the deep and superficial fascia, causing thrombosis of the affected blood vessels and necrosis of the corresponding skin, subcutaneous tissue and fascia. It can occur in all parts of the body, but is more common in the extremities, especially the lower extremities, followed by the perineum, neck, face, abdomen, back and buttocks. Who can get necrotizing fasciitis? Predisposed people: diabetes, kidney disease, immune deficiency, malnutrition, old age, intravenous drug use, long-term glucocorticoid application, chronic skin ulcers. Predisposing factors: skin abrasions, burns, puncture wounds, animal or insect bites, intravenous injections, subcutaneous injections, chicken pox What are the consequences of having necrotizing fasciitis? Skin necrosis, hyperthermia, shock, unresponsiveness or loss of consciousness, acute renal failure, multiple organ failure. How is it detected early? Typical presentation: red, swollen, hot, painful, hard skin, may have blisters. However, early onset of the disease does not always have typical symptoms, bearing in mind that abnormal pain not parallel to the skin symptoms is the characteristic manifestation of the disease. Early onset may be accompanied by a cluster of flu symptoms: i.e. fever, chills, tachycardia, muscle aches, diarrhea, vomiting. Laboratory tests and examinations: accelerated blood sedimentation, elevated leukocytes, elevated creatine kinase, hypocalcemia, abnormal blood gas analysis. x-ray, ultrasound and magnetic resonance examination reveal disorganized tissue structure, gas formation, fluid accumulation. mri examination is the most sensitive. Local exploration of the wound with Gram staining. How to treat? Supervision Apply antibiotics, be broad spectrum, take into account anaerobic bacteria Debridement and drainage Other: apply anticoagulants, immunoglobulins, hyperbaric oxygen.