Patients with infectious intoxication will have the following symptoms: 1. Usually the patient will be in a state of sympathetic excitement, still clear, but irritable, anxious, nervous, pale face and skin, mild cyanosis of the mouth, lips and nail bed, and terminal wet and cold extremities. This is accompanied by nausea, vomiting, decreased urine output, accelerated heart rate, deep and fast breathing, normal or low blood pressure, smaller pulse pressure difference, and arterial spasm seen in the microcirculation of the fundus and nail bed.2. With further aggravation of infection intoxication, the patient will become irritable and unconscious, shallow and slow breathing, low and dull heart sounds, fine and rapid pulse, decreased or even unmeasured blood pressure, cold and cyanotic skin, and more reduced urine output or even Urine output is even reduced or even absent. In the late stage, multi-organ failure and multi-organ insufficiency can occur, which can lead to acute renal failure, acute cardiac failure and acute respiratory failure in severe cases, causing death.