Since insomnia is a common symptom of anxiety and depression states, the use of antidepressants can effectively improve a variety of symptoms in patients with insomnia. 1.What are the new antidepressants commonly used? (1) Selective pentraxin reuptake inhibitors (SSRIs) There are five kinds of drugs, including fluoxetine, paroxetine, sertraline, ciprofloxacin and fluvoxamine, which are known as “five golden flowers”. They can significantly improve mood and sleep. (2) Pentoxifylline and norepinephrine reuptake inhibitors (SNRI): a newer generation of antidepressants. In addition to improving mood symptoms through pentraxin and norepinephrine in the brain, these drugs can also improve somatic symptoms (such as somatic pain, sleep disorders, appetite disorders, etc.) through pentraxin and norepinephrine in the spinal cord, representing drugs such as duloxetine, venlafaxine and mirtazapine. 2.What is the course of antidepressants? Generally speaking, new antidepressants take effect within 1-2 weeks, the most obvious effect in 1-2 months, and clinical recovery can be achieved in 2-3 months. After the first treatment, after all symptoms have improved, it is advisable to maintain the treatment with medication for 6 months to more than 1 year. The establishment of proper sleep hygiene habits while adhering to medication is the key to prevent relapse after stopping medication, and is also the most negligible basis of treatment for patients; pure medication is aimed at treating the symptoms and cannot cure the root cause. For those who have more than 2 relapses in the last 5 years, it is advisable to maintain treatment for more than 2-3 years. for those who have more than 3 relapses, it is advisable to use medication for a long time. 3.Side effects of new generation antidepressants The latest generation of antidepressants have undergone rigorous clinical trials and not only have a high clinical recovery rate, but also all side effects are controlled to a minimum, even if they are rare, they are publicly stated as much as possible. Common side effects include gastrointestinal reactions, such as nausea, dry mouth, constipation, fatigue, drowsiness, excessive sweating, and decreased appetite. Side effects mostly appear within a week, and in general, side effects largely resolve or disappear after 1 week. If side effects are significant, you should inform your doctor promptly. To reduce early discomfort, antidepressants can first take half a tablet for 6 days, and then increase to one. 4.Will antidepressants become addictive if used for a long time? Antidepressants are not addictive substances. There are two criteria for addiction: one is addiction of the heart: the psychological strong demand for the use of drugs, to the extent of recklessly looking for drugs to eat; the second is addiction of the body: the performance of the drug can not be broken, otherwise there is a life-threatening withdrawal reaction, but also the performance of the more you eat, the original dose can not achieve the original pursuit of the effect. Obviously, not wanting to take medication indicates that there is no heart addiction; antidepressants are generally reduced during the maintenance period, which is also not consistent with body addiction. In addition to establishing good sleep hygiene habits, it is advisable to discontinue antidepressants gradually and slowly in order to avoid “withdrawal reactions” when they are suddenly discontinued. It is best to do this under the guidance of a doctor. Studies have shown that long-term use of antidepressants can not only prevent relapse, but also help protect neurological function and improve cognitive function.