Cold urticaria should first be treated by keeping warm and not being exposed to cold substances, if not avoided, the effect of applying medication alone is not ideal. Secondly, the application of oral as well as topical medication, if there is recurrence of the disease, you can apply antihistamine medication, such as Ebastine tablets, 1 tablet every night, or Loratadine tablets, 1 tablet every night, or Olopatadine tablets, 1 tablet in the morning and 1 tablet in the evening, and topical medication can be applied with Furfurylate lotion. If the itching is strong, you need to use glucocorticoid ointment, hormone ointment can choose medium- and strong-acting hormone ointment. The strong-acting creams can be halometasone, clobetasol propionate or compound flumethasone, etc. The medium-acting hormone creams are mainly hydrocortisone butyrate cream and mometasone furoate. Medium-acting creams can be used on thin and tender skin areas, such as the groin, face and elbow fossa, popliteal fossa, etc., but long-term application is not recommended, the application of time will have some hormonal adverse reactions, it is recommended that the application of drugs under the guidance of a doctor to choose.