Abdominal pain is the main symptom of acute pancreatitis, and more than 95% of patients have varying degrees of abdominal pain. Most of the attacks are sudden and painful, but the abdominal pain may not be prominent in elderly and frail patients, and a few patients have no abdominal pain or only pressure pain in the pancreatic area, called painless acute pancreatitis. In the early stages of the disease, abdominal pain is usually located in the upper abdomen, and its extent is often related to the extent of the lesion. The abdominal pain is most frequent in the subxiphoid region; the right quadrant is second; the left quadrant is third; the whole abdominal pain is about 6%, and if the lesion is mainly in the head of the pancreas, the abdominal pain is in the right upper abdomen and can radiate to the right shoulder or right back; when the lesion is mainly in the neck and body of the pancreas, the abdominal pain is in the upper abdomen and subxiphoid; the abdominal pain is prominent in the left upper abdomen for caudal lesions and can radiate to the left shoulder and back; when the lesion involves the whole pancreas, the pain is girdle-like in the upper abdomen and can radiate to the When the lesion involves the whole pancreas, the pain is girdle-like in the upper abdomen and can radiate to the back. With the development of inflammation, involving the peritoneum and expanding into diffuse abdominal inflammation, the pain can involve the whole abdomen, but the upper abdomen is still dominant. The sensory nerves of the pancreas are bilaterally innervated, with the head coming from the right side, the tail from the left side, and the body by the common branches of the left and right nerves. bliss stimulated the head of the pancreas with electricity to produce pain starting from the subserous process to the right quadrant of the rib cage, stimulated the body of the pancreas to produce pain only in the subserous region, and stimulated the tail of the pancreas to produce pain starting from the subserous process to the left quadrant of the rib cage. The pain of acute pancreatitis is not only related to the extent of the lesion of the pancreas itself, but also to the extent of its surrounding inflammation. The nature and intensity of abdominal pain are mostly consistent with the severity of the lesion. Edematous pancreatitis is mostly a persistent pain with paroxysmal exacerbation, which is often tolerable. It can be relieved by antispasmodic drugs due to the presence of vasospastic factors. Hemorrhagic-necrotic pancreatitis is mostly colic and knife-like pain, which is not easily relieved by general antispasmodics. The pain can be aggravated by the promotion of digestive enzyme secretion after eating. It is aggravated when lying on the back. Patients often take the hip flexion lateral position or bend forward sitting position, in order to relieve pain. When there is a paroxysmal increase in abdominal pain, the patient shows twisting and tumbling, which is different from angina pectoris, which mostly adopts a static supine position and rarely sees tumbling. Abdominal pain may resolve within one to several days of onset, but this is not necessarily a sign of remission, or even a sign of severe deterioration.