The clinical manifestations of chronic renal failure mainly include: 1. abnormalities of the digestive system: it is the primary symptom of patients with chronic renal failure who visit the clinic. Patients mostly see nausea, vomiting and lack of food and drink, and in severe cases, gastrointestinal bleeding; 2. Cardiovascular system abnormalities: patients show symptoms such as cardiomegaly, heart failure and hypertension; 3. Neurological system abnormalities: patients mainly show uremia, uremic encephalopathy and peripheral neuritis when toxins are particularly high; 4. Respiratory system abnormalities: patients generally show respiratory distress and pulmonary edema; 5. Hematological system abnormalities. Such as anemia; 6. Others: restless leg syndrome, pruritus and hyperkalemia, etc.