Crush syndrome refers to the human limbs and trunk muscles suffer from prolonged compression by heavy objects, and a series of pathological changes can occur after the compression is lifted, clinically it mainly manifests as limb swelling, myoglobinuria, high potassium, etc. It is commonly seen in trampling events or due to mudslides and other causes of body compression, and crush syndrome occurs. Hyperkalemia is caused by prolonged muscle compression during crush syndrome, which can lead to muscle necrosis and a large amount of intracellular potassium entering the circulation. High potassium has a toxic effect on the heart and can lead to cardiac arrest or heart failure in severe cases. Therefore, if a patient with crush syndrome develops hyperkalemia, it must be treated aggressively, otherwise there can be serious consequences.