HIV patients have decreased infectiousness after standardized antiviral treatment. The specific size of infectiousness needs to be tested according to the time of taking antiviral drugs and the effect of antiviral response. HIV transmission is mainly through sexual transmission, mainly due to penile friction during sexual intercourse, resulting in micro-damage to mucosal cells and HIV transmission through wounds into the human bloodstream, mainly including needle sharing, intravenous drug injection, unregulated interventional medical operations, tattoos, etc. Vertical transmission from mother to child, the HIV virus in the mother can enter the fetus through the placenta, or the child can be infected through the birth canal during childbirth or through breast milk when breastfeeding.