High white blood cells in the urine specimen, there may be specimen contamination, this situation often does not require treatment. If there is indeed an elevation of white blood cells, it may be the presence of urinary tract infections, urinary stones and other conditions, which need to be treated accordingly according to the cause.1, specimen contamination: if the white blood cell increase is very trace, the first thing to consider is whether or not there is specimen contamination. In this case, patients often do not have the symptoms of frequent urination, urinary urgency, urinary pain. It is recommended to review the urine routine again in a short period of time, and the patient is instructed to take clean mid-stream urine. If the white blood cells return to normal, there is no need to worry too much, urge the patient to drink more water for follow-up observation can be; 2, urinary tract infections: common pathogens for Escherichia coli, Staphylococcus aureus, etc., through the urethral orifice invasion of the urethra, resulting in urethral mucosal congestion, edema, and then the release of inflammatory chemokines, the leukocytes will be gathered into the inflammatory region. With the flushing of urine, the leukocytes in the urine will be elevated. Often the patient will exhibit the bladder irritation triad of urinary frequency, urgency, and pain. It is recommended to give quinolone antibiotic treatment, such as levofloxacin. Besides, patients need to pay attention to rest, drink more water and urinate more often. Diet should pay attention to light diet, avoid spicy and stimulating food, and eat more vitamin-rich food; 3. Urinary stones: if the urine leukocyte increase is induced by stones, it is firstly recommended to choose the appropriate treatment according to the size, morphology, location of the stones and whether it causes obstruction or infection. Patients should drink plenty of water and evenly, especially 3 hours after meal is the peak of excretion, it is more important to maintain sufficient urine volume. Reasonable diet, animal protein intake should be moderate, avoid eating spinach, animal offal. In addition, you can take appropriate oral lithotripsy medication, and you can also undergo extracorporeal shock wave lithotripsy or choose minimally invasive surgery to remove stones.