The use of the Mannedrol ring for adenomyosis is useful. First of all, Manuel contains levonorgestrel, so it is also called levonorgestrel extended release system. After it is placed in the uterine cavity, it can slowly release levonorgestrel, about 20μg per day. The high local concentration of levonorgestrel in the uterine cavity, that is, the progestin, can directly act on the glands and interstitium of the endometrium, causing the endometrium to shrink, making the endometrium respond to the circulating estrogen and inhibiting the endometrial proliferation, thus reducing excessive menstruation, which is very effective. The effectiveness of the Manned Ring in treating excessive menstruation is internationally recognized. Also by shrinking the endometrium, the symptoms of dysmenorrhea are relieved. In addition it allows the release of the medicine to the foci of adenomyosis in the myometrium, causing the ectopic foci to shrink and become less active, thus reducing the degree of menstrual pain in women. It has been used in the treatment of adenomyosis for more than 10 years and has been approved by gynecologists in various hospitals in China and abroad on the basis of evidence-based medicine. Because it is valid for 5 years, after 5 years the drug is released, its effect will be reduced and the ring will be changed again. Before the application of the Manuelle ring, adenomyosis often required a hysterectomy. Thanks to the application of the Manuelle ring, the majority of young women, especially those in their 30s and 40s, can keep their uterus, and the reduction of painful and excessive menstruation is very effective.