Facial muscle spasm is a very distressing thing, and there are various ways to treat it, such as medicine, acupuncture, closure, Chinese herbal medicine, etc., which will not work. In addition, there are two effective methods, Botox injection and microvascular decompression. Today is mainly to talk about the efficacy of Botox. Botox injection is based on the point of facial twitching to choose the location of the injection. It can be injected at any twitchy part of the face, at the eyelid if the eyelid jumps, at the corner of the mouth if the mouth jumps, etc. Local Botox injection will not hurt the function of other nerves, and the bed is less traumatic and less expensive. Botox is a blocker of the neuromuscular junction, which, in layman’s terms, means cutting the nerve-muscle connection. This method prevents facial twitching by sacrificing the motor function of facial muscles. Therefore, after each Botox injection, the effect of Botox will last for about 4 months, during which the patient’s facial motor function is diminished, and over time, after several months, the Botox is absorbed and metabolized, and the condition of facial palsy will slowly improve, but when the twitching recurs, the efficacy of another injection will become worse. Therefore, Botox treatment is a stopgap measure, and later, surgery is still required.