Cough with syncope, or cough syncope syndrome, is characterized by a transient, complete loss of consciousness after coughing, not accompanied by incontinence, which can be fully recovered on its own. Some patients with respiratory diseases are prone to this symptom. 1. The main pathogenesis is still not completely clear, may be sustained violent coughing, chest pressure suddenly increased, thus reducing venous return, cardiac output decreased, ultimately leading to a sudden decrease in cerebrovascular perfusion transient syncope. It is also possible that when coughing, the pressure in the chest cavity fluctuates greatly, which stimulates the pressure receptors, causes the peripheral blood vessels to dilate, and the arterial blood pressure rapidly decreases, resulting in the phenomenon of syncope. 2. Treatment, mainly through the use of drugs such as codeine, nalcodone, benadryl, etc. to control cough. Patients should consult the respiratory department or neurology department in time, and complete relevant examinations such as electrocardiogram, electroencephalogram, brain CT, etc., so as to clarify the cause of the disease and provide symptomatic treatment. The above mentioned drugs should be under the guidance of professional doctors.