Do I need to take medication for a long time after bypass surgery? What if I run out of the medication I brought with me when I leave the hospital? Do I need to take them all the time? Coronary artery bypass surgery only solves the patient’s current heart ischemia problem and relieves angina, but does not change the causative factors of coronary heart disease. Therefore, after bypass surgery, patients still need to take medication regularly for a long time, such as aspirin and other anti-platelet drugs for life; lipid-lowering drugs for a long time according to the blood lipid control; good control of blood pressure and blood sugar; nitrates for 3 months and continue to take or stop taking them according to the recovery of symptoms after surgery; betalactam sometimes also needs to be taken for a long time (pay attention to the heart rate during taking, it needs to be reduced or stopped if it is lower than 60 beats/min. It is recommended to consult with your doctor), etc. Adjustment of the dose or discontinuation time of these drugs should be reviewed at the hospital and adjusted by your doctor. Some medications have contraindications or interactions with each other, so if you are taking other medications, it is also recommended that you go to the hospital and use them under the guidance of your doctor. Medication is the basic treatment for coronary heart disease and needs to be adhered to for a long time. For certain medications brought at the time of discharge from hospital, they are only for the early discharge period up to 3 months, and not necessarily all of them should be taken for a long time. In addition there are some drugs to control heart rate and blood pressure, which need to be adjusted regularly according to the patient’s heart rate and blood pressure changes, preferably with daily monitoring, i.e., count your own heart rate and measure your blood pressure, and you need to follow up promptly when there is a significant over or under.