High cardiac enzymes are suggestive of necrosis of cardiomyocytes, and their elevation is often a transient and dynamic process. There is no specific drug that can bring it down, but only the treatment of the cause of the disease, timely and effective management of acute myocardial infarction, myocarditis or severe heart failure, etc., cardiac enzymes will be reduced. There are many reasons for the increase of myocardial enzymes, so it is necessary to clarify the triggering factors first, and then carry out targeted treatment. For example, the increase in cardiac enzymes in acute infarction is dynamic, with a rising and falling process. Other causes such as myocarditis caused by myocardial enzyme increase can be reduced to normal in a short period of time, if the area of myocardial injury is too large and myocardial necrosis is too much, the high value of myocardial enzyme state lasts for a long time. Myocardial necrosis myocardial enzyme increase belongs to the natural process, different causes of myocardial enzyme increase, the method of fall back is similar, the main cause of treatment. For example, patients with acute ST-segment elevation myocardial infarction need to quickly open the infarction-related vessels to restore myocardial perfusion and reduce more myocardial necrosis. For this type of infarction, the sooner you get to the hospital and open the coronary artery, the better the prognosis. The clinical prognosis of pharmacologic thrombolysis and interventional therapy within 3 hours of onset is similar, but even after successful thrombolysis, intervention should be performed as soon as possible. If the onset is within 3 hours to 12 hours, intervention is preferred if the patient has no contraindications. If the time window is exceeded, conservative treatment with medication is needed for 7-10 days, and then intervention is performed depending on the patient’s condition. So the earlier and more timely the treatment, the earlier the peak cardiac enzymes will appear, the earlier they fall, the better the prognosis. Therefore, in order to bring down the elevated cardiac enzymes, the first thing to do is to clarify what causes the elevated cardiac enzymes, and then just treat the cause.