Tetanus is an acute infectious disease caused by Clostridium tetani that invades the body through a broken wound and grows and multiplies to produce toxins, and tetanus shots are usually given in the following cases 1, open injury, the wound has the possibility of contamination with tetanus bacillus, so for such wounds, especially by rusty iron injury or deeper wounds, due to the relatively large contamination of the wound, coupled with relatively little oxygen deep in the wound, very suitable for the growth and reproduction of toxins, so be sure to inject tetanus antitoxin after strict treatment of the wound, if allergic to tetanus antitoxin, you can take Desensitization method injection or switch to tetanus immunoglobulin. 2, small but deep wounds, such as stabbed by sharp objects to deeper tissue, deep and thin wounds, or traumatic wounds small and tightly bandaged resulting in local ischemia and hypoxia, also suitable for the growth of tetanus bacteria, so after the treatment of the wound, also need to inject tetanus antitoxin. 3, newborns should also be promptly injected with tetanus antitoxin after treatment of the umbilical cord to prevent the occurrence of neonatal tetanus. Overall, deeper wounds and more serious contamination increase the likelihood of tetanus, so timely tetanus injections are necessary for patients with such wounds.