The life expectancy of patients with diabetic uremia is usually affected, and active glycemic control and renal replacement therapy are usually required to slow down the disease progression and prolong life expectancy. Diabetic uremia usually means severe kidney damage due to diabetes, at this time the patient has entered the stage of end-stage renal disease, and may develop renal anemia, renal bone disease, heart failure, neurological disorders and other complications, and in severe cases, the patient may die due to organ failure and infections, so life expectancy will be affected. Patients with diabetic uremia need to strictly control blood glucose and actively perform renal replacement therapy, usually insulin can be used to lower blood glucose, hemodialysis, peritoneal dialysis, kidney transplantation and other ways to carry out renal replacement therapy, in order to slow down the development of the disease process and try to extend the patient’s life. It is recommended that patients with diabetic uremia seek immediate medical attention and follow the doctor’s instructions for standardized diagnosis and treatment.