Clinically, diabetic nephropathy is mainly staged according to Morgensen staging for proteinuria and renal function, which can be divided into 5 stages. Stage I: There is no clinical manifestation of nephropathy, only hemodynamic changes, when glomerular filtration rate (GFR) is elevated, kidney volume increases, glomerular and tubular hypertrophy. There may be transient micro-proteinuria during exercise, emergency, and poor glycemic control. Stage II: Persistent microalbuminuria, normal or elevated GFR, clinically asymptomatic. Renal pathology of glomerular/tubular basement membrane thickening and widening of the tethered zone. Stage III: Significant increase in protein albuminuria (urinary albumin excretion rate >200mg/24h, proteinuria >0.5g/24h), mild hypertension may be present, GFR decreases but blood creatinine is normal. Renal pathology shows focal/diffuse sclerosis, K-W nodules, hyalinosis of small in/outgoing glomerular arteries, etc. Stage IV: massive proteinuria, up to the level of nephrotic syndrome. Stage V: renal function continues to decline until end-stage renal disease. Diabetic nephropathy patients need to go to regular hospitals, clear staging, standardized treatment under the guidance of physicians.