To have a healthy and smart child is the wish of every couple, which is related to the prosperity of several families, even the family, and is a major human event; however, for infertile couples, it is very painful, helpless and confusing. The good thing is that there are always more solutions than problems. With the help of reproductive medicine specialists, you will find the right way for you; first you yourself must know how to seek help. Hopefully, my advice will be useful to you. 1. The concept of infertility describes a married couple who have failed to achieve natural conception within a certain period of time (usually 12 months) without the use of contraception by both partners. Infertility may be permanent or irreversible, such as some azoospermia patients are considered “absolute infertility”; may also be the possibility of natural conception decreased, but not yet down to zero, called “low fertility”. Therefore, except for the minority of azoospermia patients, most patients should have hope, please believe in this. Don’t be gullible or misbelieve, don’t suffer from natural disasters and human disasters. 2. The traditional view is that the responsibility of infertility lies with the woman. In fact, according to the World Health Organization’s research shows that more than 50% of infertile couples, men have reproductive function defects. Therefore, when each couple consults about infertility or begins to see a doctor, an evaluation of the male should follow and be implemented. Sometimes it is true that a slap in the face is not enough. 3. It is important to keep in mind that male “low fertility” is associated with one or more factors that can lead to reduced female fertility, and that the male partner should be treated at the same time as the female infertility factor. This is where the concept of co-diagnosis and co-treatment comes in. 4. Doctors should inform both infertile couples of the diagnostic procedures and treatment options. The purpose is to reduce the tension and anxiety caused to the patient during the diagnosis and treatment. In addition to strategic secrecy, the doctor must let you understand what you are going to do next and what the end result will be. Nonsensical cloudiness definitely does not bode well for anyone. 5. The choice of treatment options should adhere to the principles of evidence-based medicine (based on rigorous RCT trials that are credible) and take into account cost-effectiveness, and must take into account the ethical, religious and emotional aspects of the couple. 6. Meta-analysis (a common method of analysis in evidence-based medicine) has shown that controlled studies, prospective cohort studies, and especially randomized prospective studies that have been done so far have confirmed that the success of treatment for male infertility is significantly correlated with female fertility. Examining the field of reproductive medicine from an evidence-based medicine perspective, especially the diagnosis and management of male infertility, reveals that highly reliable treatment options are very limited. That is why it is important to find the right program, with the relevant experience, technology and tools, to diagnose and treat infertility.