Diagnosis and treatment of plasmacytoid mastitis

  The incidence of plasmacytoid mastitis has long been thought to be low, but it is not. The reasons for the “low” incidence are as follows: 1. The name of the diagnosis is not uniform around the world and is still controversial. Each speaks its own language, which artificially causes the “perception” of low incidence. The name of the disease used in our mammary department is “plasmacytosis mastitis”, which may not be used in other provinces or even in other hospitals in the city; the name of the disease in Chinese medicine is “acne canker sore”, which is also not found in ancient Chinese medical texts and was created by my mentor, Mr. Gu Bohua, in Shanghai. The name “acne vulgaris” is also not found in ancient Chinese medical texts, but was created by my mentor, Mr. Gu Bohua. Personally, I think that if all non-lactating mastitis is grouped into one category – ductal dilation of the breast. The incidence is not very low.  2, many women (male patients also, very rarely) found a breast lump, in various hospitals, or medication or surgery to obtain a cure, but at that time the doctor did not give a clear diagnosis, the disease is well and did not pursue what it is. Statistically speaking it was missed.  Second, the cause of morbidity Strictly speaking, all diseases that are not injected after birth, the cause of morbidity is still unclear, common, such as hypertension, diabetes, terrible, such as a variety of cancer are such. The current causes or predisposing factors are the result of long-term observation of cases by medical personnel, which is strictly an “inference” rather than direct evidence. In the case of plasmacytoid mastitis, patients with sunken nipples, localized trauma to the breast, high prolactin levels or clear pituitary tumors are more common. The younger patients tend to develop a larger range of lesions at once, while older patients have a relatively limited range of lesions.  Clinical manifestations Initially, the patient may only have a lump in the breast, or it may be accompanied by redness and swelling of the breast skin, which is not particularly typical and misdiagnosis is very common. In some cases, the lump resembles breast cancer, and the imaging examination also suggests “breast cancer”, but the diagnosis of “inflammation” is not confirmed until the pathological examination by puncture. Therefore, the experience of the doctor is important in the early stage of the disease. In early stage patients, if medication is administered promptly, surgery can be avoided much more often than after the disease has progressed. Most commonly, patients have progressive enlargement of the lesion, which manifests as red, swollen and ulcerated skin.  IV. Examination Plasmacytic mastitis is non-bacterial, so laboratory tests for blood leukocytes are often not high. Instead, sex hormone indicators, especially prolactin levels, need to be checked, and some indicators related to immunity also need to be checked. In terms of imaging, ultrasound and MRI are more appropriate, while mammography is often more aggravating because of the need to squeeze the breast. Of course, the final diagnosis relies on pathological sections.  V. Treatment Some diseases have gained consensus among medical professionals, such as acute appendicitis requiring appendectomy, hernia requiring hernia repair to strengthen the weak area, and uremia requiring hemodialysis. There are also some complex diseases for which consensus has not yet been achieved. Plasmacytoid mastitis is precisely such a disease. The reason for this analysis is that all treatments have advantages and disadvantages, there are no absolute advantages and all have disadvantages. Simply put, there is no very perfect treatment. The following treatment methods are now applied: 1. Remove most of the diseased tissue, traditional Chinese medicine open wound change. Disadvantages: the treatment time is longer, the pain of changing medicine is greater; sometimes the treatment process requires another surgery on the patient’s psychological blow.  2.Complete removal of lesion tissue, direct suturing of the incision. Disadvantages: more tissues need to be removed, in case they are not cleared and sutured, it is easy to recur and lead to another operation which is a big psychological blow to the patient.  3.Non-surgical treatment, long-term conservative Chinese medicine. Disadvantages: conservative often need more than 6 months to see whether there is a curative effect, if you adhere to a long time but eventually need surgery, the patient psychological blow is larger.  4, foreign countries believe that this disease belongs to autoimmune diseases, often apply corticosteroids and immunosuppressive therapy. Immunosuppressants are sometimes used in patients with malignant tumors, and Chinese people often refuse to see “hormones” and “chemotherapy drugs”. In fact, in many cases, corticosteroid and immunosuppressive therapy are effective.  The psychological impact on the patient is very important in all of these approaches, because plasmacytosis is a benign disease that is not fatal in the end, and 40 years ago it was treated with mastectomy, which was not recurrent and acceptable to the patient. But today, the vast majority of patients would not want to have their breasts removed. It is important to understand, then, that as long as the breast exists, the chance of recurrence of the same disease exists. Many patients are treated in some way and find it difficult to accept that the disease has recurred after they have already suffered a lot. As already stated, the cause of the disease is not clear and there is no preventive shot, so none of the above methods have eliminated the recurrence of the disease.