How thyroiditis is caused

  Thyroiditis refers to inflammation of the thyroid gland and is not a disease, but a group of diseases that are clinically divided into several types, each with different causes. The common types are: subacute thyroiditis: also known as granulomatous thyroiditis, cytomegalic thyroiditis, the onset is related to viral infection and is self-limiting. 10%-20% of patients can find thyroid autoantibodies in the subacute phase, such as influenza virus, coxsackie virus, adenovirus, mumps virus, but the antibodies also disappear after the disease remits, and the vast majority can be cured in a few days, usually without There are no residual symptoms. The disease is most common in adults aged 30-50 years and is more common in women than in men.  Autoimmune thyroiditis: Common types of the disease include Hashimoto’s thyroiditis, atrophic thyroiditis, quiet thyroiditis, postpartum thyroiditis, drug-related thyroiditis, and Hashimoto’s thyrotoxicosis. The common features are mainly the presence of antibodies against the thyroid gland itself in the serum and the presence of infiltrating lymphocytes in the thyroid gland, which is a major type of thyroiditis associated with an autoimmune response, but the degree of thyroid destruction is not necessarily proportional to the symptoms of hypothyroidism.  Painless thyroiditis: infiltration of thyroid lymphocytes is mild, with only focal infiltrates that manifest as transient, reversible destruction of thyroid follicles. In half of the patients, the thyroid gland presents with mild enlargement, diffuse, hard texture, and no local tenderness. The thyrotoxicosis of this disease is caused by the destruction of thyroid follicles by inflammation and leakage of thyroid hormones into the circulation. Postpartum thyroiditis is also a variant of painless thyroiditis.  Acute septic thyroiditis: It is a rare or rare inflammation of the thyroid gland, commonly seen in pediatric patients, mostly due to abnormal development of the thyroid gland or with other abnormalities of the neck, followed by a bacterial infection, such as abnormal development of the cheek cleft. The local manifestation is a painful mass on palpation of one side of the thyroid gland, with congested, red skin, intense pressure pain and high tension. It can have an acute onset, with high fever and blood work consistent with septic inflammatory changes, but the nail function is generally normal.  Therefore, thyroiditis is a group of diseases with different types of thyroiditis with different symptoms. Clinical treatment also requires that the type be determined by examination before the correct treatment can be administered.  In summary, the disease usually lasts for several weeks and most resolve on their own, but can recur. Most thyroid function returns to normal, with some patients experiencing transient hypothyroidism, which rarely progresses to permanent hypothyroidism.