Myasthenia gravis is an autoimmune disease that damages the nerve junction (neuromuscular end plate) and is originally an uncommon disease, the cause of which has not been fully understood. There are many studies on the treatment of this disease, but there are no results yet, and some are only at the stage of clinical trials. The accepted treatment method at home and abroad is a comprehensive treatment including medical drugs, serum and immunosuppressive therapy, radiation therapy, herbal medicine and surgical treatment. Among them, surgical treatment plays a significant role. Most patients with myasthenia gravis often consult ophthalmology or internal medicine first because of ocular muscle paralysis, while many clinical non-neurology or thoracic surgeons are not clear about the treatment principles of myasthenia gravis, let alone the significance of thymectomy for the treatment of myasthenia gravis. In addition, many non-specialized hospitals are not capable of handling the diagnosis, examination and treatment of myasthenia gravis and various complicated complications such as myasthenia gravis crisis due to the limitation of conditions and experience, resulting in the deterioration or prolongation of the disease and serious loss of working life due to the failure of timely and correct diagnosis and standardized treatment of a considerable number of patients. Some of them blindly seek medical treatment, but do not get real cure and relief, but lose a lot of money for nothing, and they are cheated by witch doctors. In our hospital, there are also many patients with ophthalmic myasthenia gravis who often mistakenly think that they are suffering from eye disease in the early stage of the disease, and often go to the ophthalmology department first, but when it is found to be myasthenia gravis, they think that the disease of ophthalmic myasthenia gravis is very light, and only make general symptomatic treatment for a long period of time, which inadvertently delays the disease and misses the best time for surgery, and even eventually transforms into a systemic type or is forced to operate only when it is complicated by thymoma. The treatment effect is of course greatly reduced. When it comes to thymectomy for myasthenia gravis, it has a long history. The relationship between the thymus and myasthenia gravis has been noticed since 1901. In 1912, the thymus gland was first resected abroad to treat myasthenia gravis, with more satisfactory results. In 1939, Blalock first successfully treated myasthenia gravis with simple thymus removal via median sternotomy, and provided the theoretical basis for the surgical treatment of the disease. Nowadays, thymectomy is recognized as a more effective treatment for myasthenia gravis. It is also believed that surgery should be performed early once the diagnosis is confirmed, because the shorter the medical history, the better the surgical results. On the contrary, the longer the history of the disease, the worse the treatment effect. For many years, domestic and foreign hospitals and thoracic surgeons mostly use the traditional open thoracotomy surgery. However, this surgery requires splitting through the middle of the sternum (as shown in the figure), which causes great damage and a large postoperative incision scar that seriously affects the aesthetics, and is prone to postoperative crisis, pulmonary impairment, phrenic nerve injury, mediastinal and intrapulmonary infection and other complications, which is often difficult for patients to accept. In order to solve these problems, other different surgical approaches have been used, but they were abandoned due to the difficulty of exposure and incomplete resection. Nowadays, minimally invasive surgery, represented by thoracoscopy, has shown great superiority. It has the advantages of small trauma, light pain, fast recovery, reliable efficacy, and the incision is both small and concealed to meet the cosmetic requirements, which completely meets the requirements of patients for health and beauty. In particular, modern thoracoscopy has expanded the surgical field of view, and the wide screen display makes it easier for the surgeon to operate and cooperate, while shortening the operation time and the average hospital stay. Since 1996, the procedure has been carried out in the United States, Southeast Asia and Hong Kong, and has achieved very satisfactory results and is very popular among patients and doctors. The Department of Thoracic Surgery of Beijing Tongren Hospital, in cooperation with the Department of Ophthalmology and Neurology, has been treating a large number of such patients throughout the year, and has fully developed and mastered various techniques of thymectomy, accumulating rich experience in surgery and treatment. For several years, we have been the first in China to carry out thoracoscopic surgery for myasthenia gravis. We have adopted different surgical methods to treat myasthenia gravis for various types of patients, and have cooperated closely with neurology and surgical care units to form a comprehensive treatment system, which has achieved satisfactory results and is a leading position in China. At present, TV-assisted thoracoscopic thymectomy and minimally invasive small-incision thymectomy have been listed as a mature technique and are routinely performed in our department.