Ectopic pregnancy in a 27 year old woman, medication to help!

(Disclaimer: This article is for general use only. The following information has been processed to protect patient privacy. The patient reported that she was not using contraception and started with persistent vaginal bleeding followed by abdominal pain. The diagnosis of ectopic pregnancy was made by monitoring positive blood HCG and ultrasound suggesting a mass in the adnexal region. With a stable condition and low blood HCG level, the patient was treated effectively with conservative medication with progressive decrease in blood HCG and ultrasound suggesting reduction of tubal masses. Basic information】Female, 27 years old 【Disease type】Ectopic pregnancy 【Hospital】Jiangbin Hospital of Guangxi Zhuang Autonomous Region 【Time of consultation】December 2021 【Treatment plan】Medication (mifepristone tablets, methotrexate for injection) 【Treatment cycle】Hospitalization for 7 days, regular follow-up 【Treatment effect】Progressive decrease in blood HCG, ultrasound suggesting reduction of tubal mass, effective treatment I. Initial The patient came to our hospital in December 2021. She described herself as having had 2 previous abortions, regular menstruation, no dysmenorrhea, and no contraception. On November 5, 2021, her last menstrual period started to bleed vaginally for 35 days without any other discomfort, so she thought she was menstruating and did not go to the hospital. She was diagnosed with ectopic pregnancy. She was diagnosed with “ectopic pregnancy” and admitted to the hospital. (Three outpatient pregnancy tests on December 19) After admission, the patient was given routine blood tests, liver and kidney function, coagulation function and electrocardiogram, and no significant abnormalities were found. Therefore, she explained to the patient that according to the current examination results, she was considered to have a right-sided tubal pregnancy, which could be treated by laparoscopic surgery or conservative drug treatment. The patient chose conservative treatment after discussion with her family. Mifepristone tablets + methotrexate for injection were given immediately. The patient was also informed that drug treatment may not be successful in every case, so she should be closely monitored by ultrasonography and blood HCG during treatment and pay attention to drug side effects. During the conservative treatment of drug embryo killing, the patient’s vital signs were monitored normally, the patient had occasional mild abdominal pain and no increase in vaginal bleeding. 7 days later, the routine blood test showed no decrease in hemoglobin compared with the admission, and the blood HCG was 217.37mIU/ml. In comparison with the previous findings, the patient’s blood HCG decreased after treatment, the tubal mass decreased, and there was no abdominal bleeding or signs of ectopic pregnancy rupture, indicating that the conservative treatment was effective. Unfortunately, the patient developed ectopic pregnancy, but fortunately the treatment was timely and no serious condition such as tubal rupture occurred. After discharge from the hospital, the patient should be observed for any increase in abdominal pain or vaginal bleeding, and return to the hospital immediately if necessary, as well as for regular follow-up to avoid any abnormalities. During the recovery period, pay attention to more rest, avoid sexual intercourse, keep the vulva clean to avoid upstream infection, which may lead to endometritis or other pelvic inflammatory diseases; avoid strenuous exercise and eating stimulating food to avoid discomfort to the organism. V. Personal insight Ectopic pregnancy usually refers to the development of a fertilized egg in the uterus outside the body, as in the case of this patient, a tubal ectopic pregnancy. The main manifestations are menopause, abdominal pain, and irregular vaginal bleeding. However, it should be noted that the success rate of drug treatment is not 100%, so it is necessary to closely observe the changes in the condition and the toxic side effects of the drugs after administration. If the condition does not improve, or even if acute abdominal pain or tubal rupture symptoms occur, surgery should be performed immediately.