Patients with perianal hard lumps, may be caused by perianal abscess, hemorrhoids, anal fistula and other diseases, need to choose different treatments according to the different causes, the early patients can use drugs including acetaminophen and other pain relievers, metronidazole and other antibiotics, as well as hemorrhoids blood capsules and other traditional Chinese medicine. 1. perianal abscess: perianal abscess patients early, can follow the doctor’s instructions to take antibiotics, such as piperacillin, ceftazidime, etc.; for special types of perianal abscess can be used metronidazole and oxfloxacin, etc., for treatment, the patient can also be used to potassium permanganate diluted solution for cleaning or sitz bath. 2. Hemorrhoids: hemorrhoid patients can use painkillers, such as acetaminophen, ibuprofen, etc.; antibiotics, such as metronidazole, cefixime, etc.; traditional Chinese medicine, such as hemorrhoidal blood capsule, locust pills and other medicines for treatment, but also local use of Ma Yinglong hemorrhoid cream, taining suppository for treatment. 3. anal fistula: patients can follow the doctor’s instructions to use antibiotics, such as cefixime, metronidazole, etc.; or the use of such as hemp pills, lactulose oral solution, etc. for treatment; patients can also use potassium permanganate solution, mupirocin ointment, fusidic acid cream, etc. for local treatment. It is recommended that patients strictly follow the doctor’s prescription of medication, actively cooperate with the doctor’s treatment, pay attention to monitoring the condition in life, if the condition worsens should seek medical treatment in a timely manner.