Clinically, after the consumption of vitamin B2, the metabolites will lead to yellowing of urine, which is a normal phenomenon after the metabolism of the drug, so there is no need to worry. Vitamin B2 is generally used for the treatment of stomatitis, tongue inflammation or seborrheic dermatitis, including other skin inflammations, etc. Because vitamin B2 can maintain the integrity of the skin mucosa and is mainly involved in the metabolism of fat and protein in the body, it can improve the metabolic rate. Therefore, vitamin B2 supplementation is recommended for patients who have been eating poorly for a long time or who have recently had a cold, poor nutrition and poor immunity, otherwise the patients are very prone to orchitis and orofacial fissures. The more commonly used foods for vitamin B2 supplementation are animal offal, such as liver, or green leafy vegetables and cereals. Therefore, it is important to note that vitamin B2 must be properly supplemented to be able to prevent the disease.