Hematuria that needs to be taken seriously We often see patients with hematuria in the clinic, but unless there is a lot of bleeding, most of them do not take it very seriously. There is a fear of hematuria and avoidance of medical attention; there is also a reason why hematuria presents mostly sporadically. However, hematuria, especially in those over 40 years of age who do not have pain, needs to be examined carefully. This is because the causes of painless hematuria are often related to urological tumors and male prostate enlargement. Urological tumors, when treated with delay, can seriously affect the outcome of treatment and the patient’s health. Bleeding in men with prostate enlargement, on the other hand, often leads to clot formation and bladder blockage, causing a vicious cycle that aggravates the bleeding and may eventually require emergency surgical treatment. Therefore, anyone over the age of forty who develops painless hematuria needs to be seen promptly to identify the cause and not be taken seriously!