Colitis does not heal on its own without medication and occurs mainly in young and middle-aged patients, and the exact causative agent is unknown. It is considered an autoimmune disease, most commonly ulcerative colitis, in which patients experience significant abdominal pain, bloating, diarrhea, nausea, vomiting, blood in the stool, and even mucopurulent stools, and repeated episodes can also lead to anemia and disruption of the internal environment. Ulcerative colitis is also prone to malignancy, with anemia, weight loss, and extensive metastasis in the abdominal cavity. Early diagnosis should be promptly selected for treatment, oral azathioprine in combination with salazosulfapyridine, and attention to diet, away from stimulating foods, away from the environment of tobacco and alcohol, appropriate abdominal massage, and regular colonoscopy.