The liver is the main organ of the body’s lipid metabolism, intrahepatic fat mainly from food and peripheral adipose tissue, resulting in abnormal mechanisms of metabolism of lipid deposition in hepatocytes is not completely clear, it is currently believed that the formation of fatty liver is related to the following factors. 1, obesity The degree of fat accumulation in the liver is proportional to body weight. 30% to 50% of obesity is combined with fatty liver, and the rate of fatty liver lesion in heavy obese people is as high as 61% to 94%. Obese people’s weight is controlled, its fat infiltration is also reduced or disappeared. 2, alcohol long-term alcoholics liver puncture biopsy, 75% to 95% have fat infiltration. Others observed that drinking more than 80 to 160 grams of alcohol per day, the incidence of alcoholic fatty liver increased by 5 to 25 times. 3, rapid weight loss Fasting, excessive dieting or other rapid weight loss measures can cause a large increase in lipolysis in the short term, consuming glutathione in the liver, causing a large increase in malondialdehyde and lipid peroxides in the liver, damaging liver cells and leading to fatty liver. 4, malnutrition malnutrition leading to protein deficiency is an important cause of fatty liver, mostly seen in insufficient food intake or digestive disorders, can not synthesize apolipoproteins, resulting in triglyceride accumulation in the liver, the formation of fatty liver. 5, diabetes about 50% of diabetic patients can occur fatty liver, with more adult patients. Because 50% to 80% of adult patients with diabetes are obese, their plasma insulin levels and plasma fatty acid increase, fatty liver change is related to both the degree of obesity, but also with the consumption of fat or sugar too much. 6, drugs certain drugs or chemical toxins through the inhibition of protein synthesis and fatty liver, such as tetracycline, adrenocorticotropic hormone, puromycin, ring has been amine, spit root base and arsenic, lead, silver, mercury, etc.. Lipid-lowering drugs can also form fatty liver by interfering with the metabolism of lipoproteins. 7. Pregnancy Most of the disease develops at 34-40 weeks of gestation in the first child, with serious illness and poor prognosis, with maternal and infant mortality rates of 80% and 70% respectively. 8, other infections such as tuberculosis, bacterial pneumonia and sepsis can also occur fatty liver, viral hepatitis patients who excessively restrict their activities, coupled with the intake of high sugar, high calorie diet, liver cell fat accumulation; after receiving corticosteroid treatment, fatty liver is more likely to occur. There are also so-called extra-gastrointestinal hypertrophic fatty liver, toxic fatty liver, fatty liver caused by hereditary diseases, etc.