On the issue of malignant nevi. The incidence of malignant melanoma accounts for only about 5% of skin malignancies, but constitutes 75% of their mortality. Such a serious malignant tumor may come from the moles that can be seen everywhere on the body. In the consultation, we always encounter many people asking, “Will a small mole suddenly appear on my face and turn into cancer?” “I have a mole with hair on it, is it likely to become malignant?” Myth 1: Can a mole (intradermal mole), especially a mole with hair, become malignant? Many patients are particularly worried when they see raised moles (intradermal moles), especially those with long hairs, and think that they will become malignant. Of course, congenital giant moles are most likely to become malignant. In addition, moles located on the soles of the feet and the palms of the hands and other abrasive parts are also relatively easy to become malignant, and malignant melanoma in Chinese people is most common in the hands and feet. Myth 2: Many people think that acquired moles (grown after birth) are more likely to become malignant than congenital moles (present at birth) Many people think that acquired moles (grown after birth) are more likely to become malignant than congenital moles (present at birth), but in fact, congenital moles are more likely to become malignant, and the malignancy rate of congenital small moles is about 1%, while the malignancy rate of congenital giant moles is 10-30%. Congenital nevi should be followed up regularly, and if abnormal changes are found, they should be removed surgically and examined pathologically in time. If new black “nevus”-like damage appears after the age of 40, it may be malignant melanoma or basal cell carcinoma, which requires vigilance. Myth 3: Darkening of moles = malignant change? The darkening of pigmented moles is not exactly a sign of malignant change: in summer and autumn, when there is sufficient holiday light and the influence of ultraviolet rays, the skin color of human body is obviously deeper than in winter and spring, and pigmented moles will become darker and larger accordingly; during pregnancy, puberty or taking corticosteroids or oral contraceptives, all pigmented moles can become darker and have a tendency to increase in size. Myth 4: Laser mole spotting is simple to do casually Any moles suspected of malignant possibility should never be treated with laser. Because if the mole is malignant, then the stimulation of laser will promote the metastasis and spread of cancer cells, which is not worth the loss. For those suspected of malignancy or not cleanly removed by laser, it is best to remove them surgically and have pathological tests if necessary.