The treatment of knee pain is mainly based on conservative treatment and surgical treatment for the cause of the disease. When knee pain is accompanied by fever, low fever, fatigue, muscle weakness and other systemic symptoms, it is necessary to actively target the cause and the original disease for treatment. 1.Conservative treatment. Including prohibition of weight-bearing activities on the ground, local physiotherapy hot packs, nutrition of articular cartilage, inhibit inflammatory response, if necessary, can be performed intra-articular injection of sodium vitrate treatment, can also continue to nutritional bone treatment. Generally, after 2-4 weeks of conservative treatment, the pain will be gradually relieved, if it continues to be unrelieved, it is necessary to further review the knee joint MRI or arthroscopy to clarify the diagnosis and treatment. In addition, for infectious diseases such as tuberculosis of the knee joint, we need to actively control the primary disease and carry out active treatment such as knee joint irrigation and local medication. 2.Surgical treatment. Including arthroscopic surgery and knee replacement surgery. Knee arthroscopic treatment according to the cause of knee joint cleaning, synovectomy, free body removal surgery, meniscus revision surgery, meniscus suture surgery and so on. The above are the common diseases and treatment programs for knee pain, after systematic treatment if the condition is not relieved, further examination is needed to actively treat the cause and symptoms.