It is possible for some hepatitis B carriers to recover on their own. Over time, as the body’s immune system improves, a small percentage of hepatitis B virus carriers can turn the hepatitis B surface antigen negative on their own, but the probability of this happening naturally is very low. What is a hepatitis B carrier? It refers to hepatitis B virus (HBV) infected patients who have been positive for HBsAg for more than half a year, seldom suffer from symptoms and show signs of liver disease, and have normal liver function tests. Most of them have two detectable antigens in their serum: surface antigen and e antigen, both of which are markers of the hepatitis B virus. The surface antigen is a component of the outer membrane of the virus, and the e antigen is the core component. e antigen is easier to turn negative, but the surface antigen is more difficult or takes longer to turn negative. Although there are no symptoms, signs, or abnormalities in physical or chemical tests other than carrying the hepatitis B virus, most liver tissue changes occur in hepatitis B virus carriers. Theoretically most hepatitis B carriers do not need treatment. However, long-term dynamic examination and liver tissue examination are needed. Therefore, although some patients with hepatitis B carriers can heal themselves, the chance of turning negative is very low. Therefore, hepatitis B patients should not put all their hopes on self-healing, but should actively receive treatment to avoid delaying their condition.