Since there is no drug at home or abroad that can completely kill the hepatitis B virus, it can only maximize the suppression of the hepatitis B virus, delay and reduce the occurrence of liver inflammation, cirrhosis and hepatocellular carcinoma, so as to improve the quality of life and survival time. Currently, there are two major types of drugs for the treatment of hepatitis B: interferon and nucleoside (acid) analogs. The former does not directly kill or inhibit the virus, but kills the virus and inhibits viral replication by strengthening the activity of the body’s natural killer cells, but it requires long-term injections, is expensive, and the patient’s compliance is poor, so the application effect is not good. The latter can directly inhibit the virus, long-term application can significantly improve the process of liver fibrosis, the first three months of treatment should be rechecked every month for liver function, and later review can be changed to once every three months. Most patients need to take the drug for a long time until obtaining HBsAg conversion. As for patients with hepatitis B cirrhosis, drug discontinuation is not recommended for both compensated and decompensated stages, and oral nucleoside analogs are recommended for life. Traditional Chinese medicine and herbal preparations for the treatment of chronic hepatitis B are widely available in China, but they must be dialectical and precise. Herbal preparations can enhance the physique of hepatitis B patients and strengthen the ability to resist diseases, thus promoting the immune system to clear the virus. Therefore, for the treatment of hepatitis B, patients must follow the doctor’s instructions and actively cooperate with the doctor in order to achieve the best results.