Two years after weaning, squeezing out yellow sticky liquid is mostly clinically classified as nipple overflow, and the more common causes mainly include cystic hyperplasia of the breast, intraductal papilloma, plasmacytoid mastitis, breast cancer and other diseases. It is recommended that patients should seek medical advice and improve breast ultrasound and mammography to make a clear diagnosis and take appropriate treatment measures: 1. Cystic hyperplasia of the breast: mostly due to the imbalance of estrogen and progesterone ratio, mainly manifested as lumps that appear and recede with the menstrual cycle, breast swelling and pain, etc. A few patients may also have nipple overflow, which can be treated with vitamins and hormone-suppressing drugs; if the treatment is not effective or The symptoms of nipple overflow usually disappear with surgery if the treatment is not effective or if there is a tendency of malignancy; 2. This disease is mostly associated with impaired ductal drainage, bacterial infection, and abnormally high levels of lactogen, and can be increased by local trauma, surgery, and smoking. The clinical treatment is mainly surgical and can be supplemented by antibiotics such as penicillin and metronidazole. 4. Breast cancer: the causes are mostly related to abnormal estrogen level, radiation, early menarche, late menopause, late marriage and pregnancy, long-term fat diet, mental depression, etc. The main symptom is painless lump in the early stage, with the development of cancer invading the surrounding tissues, the nipple can be flattened, sunken or retracted, and the skin With the development of the disease, the nipple may be flattened, sunken or retracted, and the skin may show dimple sign and orange peel-like changes, etc. The cancer invading the breast duct may also show nipple overflow. The lesion should be surgically removed as soon as possible, and adjuvant treatment such as radiotherapy and immunotherapy should be chosen according to the patient’s specific condition to consolidate the treatment effect. In addition, old stagnant milk, brain diseases such as prolactinoma, hyperpituitarism, endocrine system diseases such as hypothyroidism and adrenal tumor, abnormal prolactin secretion due to long-term use of contraceptives and other hormonal drugs, as well as severe mental trauma may lead to increased prolactin and thus cause nipple overflow, and it is recommended to seek medical examination to help confirm the diagnosis.