Trigeminal neuralgia, commonly known as “face pain,” is a severe pain like electric discharge that occurs repeatedly on one or both sides of the face. Trigeminal neuralgia is a neurological disorder that affects the middle-aged and elderly, mostly women, and is often unbearable. The pain can be triggered by talking, brushing teeth or breezing, and lasts for several seconds or minutes. It is called the “No. 1 pain in the world”. Trigeminal neuralgia can be divided into two categories: primary trigeminal neuralgia and secondary trigeminal neuralgia, of which primary trigeminal neuralgia is more common. The most effective drug treatment is carbamazepine. However, carbamazepine has more side effects, the common ones are: dizziness, drowsiness, weakness, nausea, rash, vomiting, occasional granulocytopenia, reversible thrombocytopenia, and occasional allergic reactions. Radiofrequency Targeted Thermal Coagulation Technology for Trigeminal Neuralgia Radiofrequency Targeted Thermal Coagulation Technology therapy is to send out high frequency radiofrequency current through radiofrequency instrument, which causes ion movement and frictional heat in the target tissues and thermal coagulation destroys the tissues and nerves in the target area, destroys the pain conduction pathway, so that it cannot be transmitted to the brain and cannot produce pain sensation, thus achieving the purpose of pain control. At present, radiofrequency targeted thermal coagulation technology therapy is more widely used in the clinic, and the treatment effect is good, and the therapy is easy to operate, can be repeatedly implemented, and can ultimately achieve the purpose of analgesia, which is the most ideal choice for trigeminal neuralgia patients. Features of radiofrequency targeted thermal coagulation technology I. Safety: precise positioning, high selectivity. Avoid the danger of traditional open surgery treatment. Punctured under image monitoring, the RF needle tip reaches the lesion directly and makes the patient’s pain symptoms disappear quickly by selectively blocking the nociceptive fibers of the trigeminal nerve. Second, minimally invasive: the incision is only the size of a needle eye, leaving no scar. At the same time, by controlling the radiofrequency temperature, it not only precisely controls and protects the nerve of the injury foci, but also greatly reduces the damage to other normal nerve tissues. Third, the treatment effect is effective: the recurrence rate is low, and there are few complications. After the surgery, the pain symptoms disappear quickly, with fast results and good efficacy. Indications for radiofrequency targeted thermal coagulation technology I. Obvious adverse drug reactions to carbamazepine and other painkillers; II. Patients who relapse after controlled radiofrequency thermal coagulation treatment can undergo coagulation treatment again; III. Patients who relapse after open trigeminal nerve vascular decompression; IV. Patients who are unwilling to undergo open trigeminal nerve vascular decompression; V. Primary trigeminal neuralgia with unsatisfactory effect by taking medication.