Symptoms of severe fatty liver disease include endocrine disorders, nausea and vomiting, and right upper abdominal pain. 1. Endocrine disorders: boys may have breast development, testicular atrophy, impotence, etc.; women may have irregular menstruation and amenorrhea. 2. Nausea and vomiting: as severe fatty liver will lead to liver function damage, nausea, vomiting, aversion to oil and smoke, abdominal distension, loss of appetite and other symptoms may occur. 3. Upper right abdominal pain: when there is severe fatty liver, there is often vague pain in the upper right abdomen, and when it is severe, the pain will be obviously aggravated, and even make the patient unbearable, which may be accompanied by symptoms such as fatigue, whitening of the skin, yellowing of the urine, and spider nevus in the palm of the hand. When the symptoms of severe fatty liver appear, it is recommended that the patient should seek medical examination and treatment as soon as possible to avoid adverse effects.