The gallbladder is one of the organs of the body and is mainly responsible for the secretion of bile. The normal thickness of gallbladder wall is 1-2mm, and most of them are 1mm. if ultrasound indicates that the thickness of gallbladder wall is more than 3mm, patients are mainly considered to have chronic cholecystitis, adenomyosis of gallbladder, other diseases, etc. Patients need to clarify the cause through gallbladder ultrasound, liver function and other related examinations. 1. chronic cholecystitis: due to infection, stones and other reasons, patients have chronic cholecystitis, and the wall of gallbladder appears fibrous scar Proliferation, and then thickening. If the symptoms are serious, the gallbladder will lose some of its diastolic and contractile functions, the gallbladder storage capacity decreases, and then the patient’s digestive function is affected, and nausea, vomiting and loss of appetite are likely to occur. If the inflammation recurs, surgery is often required; 2, adenomyosis of the gallbladder: this disease is a proliferative disease of the gallbladder, mainly chronic hyperplasia, and some patients are accompanied by cholecystitis or gallstones. In daily life, some patients may have abdominal pain symptoms, but some patients do not have any discomfort, and the thickening of the gallbladder wall can only be found during physical examination or relevant examination, and treatment or therapy is needed if necessary; 3, other diseases: if patients have hypoproteinemia, viral hepatitis, cirrhosis, hepatic ascites, gallbladder polyps, gallbladder cancer and other conditions, the symptoms of thickening of the gallbladder wall can also appear. Patients need targeted drug treatment or surgery under the guidance of professional doctors.