Renal insufficiency may cause pubic itching, but gynecological diseases need to be excluded. Renal insufficiency renal excretory function is impaired, the body metabolic waste and water discharge obstacles, can lead to creatinine, urea elevation, toxin accumulation leads to itching; at the same time the kidney phosphorus excretion is reduced, the blood phosphorus is elevated, can also lead to itching. Therefore, renal insufficiency may lead to pubic itching. However, female patients need to exclude gynecological diseases, such as vulvovaginitis, vaginitis, etc., which may also lead to vaginal itching. Renal insufficiency patients who have pubic itching, it is recommended to go to the regular hospital in a timely manner, improve the examination to clarify the cause of the disease, under the guidance of the doctor to give targeted treatment or treatment.