Meige syndrome, also known as idiopathic blepharospasm-oral mandibular dystonia syndrome, was first described by French neurologist Henry Meige in 1910 and is a relatively rare clinical dystonia disorder that mainly involves the eyelid and oral mandibular muscles, but can also be accompanied by spastic dystonia of the neck, trunk or other muscles. Meige’s syndrome is an adult-onset limited dystonia with an insidious onset in middle and old age. The age of onset and gender differences indicate that Meige syndrome is more common in middle-aged and older adults and in women. Meige syndrome is characterized by bilateral symmetrical, paroxysmal tonic contractions of the affected muscle groups, with spasms lasting from a few seconds to half a minute and stopping abruptly after 10 to 20 episodes, with no motor system abnormalities during the interval, or in severe cases, with prolonged spasms. It is worth noting that the typical spasm is often preceded by local discomfort of the affected area, such as irritation of one or both eyes, dry eyes, photophobia, and increased transients before the eyelid spasm, and tightness and discomfort around the mouth or neck before the spasm of the submandibular and cervical muscles, followed by blinking, mouth opening, pouting, lip contraction, teeth clenching, and slanting neck; in severe cases, the spasm persists and can cause functional blindness. The symptoms are aggravated by fatigue, stress and anger, and are relieved after rest and disappear during sleep. It has been reported that chewing betel nut, tobacco and other irritants are prone to Meige syndrome, which may be induced by local irritation or certain chemical substances. It has been reported that 1/3 of Meige syndrome has emotional disorder. Previously, it was thought that the dystonia in Meige syndrome mainly involved the orbicularis oculi, mandibular muscles, tongue muscles, and occasionally the neck, trunk, and other midline areas of dystonia. Most scholars classify Meige syndrome into blepharospasm, oro-mandibular dystonia, and blepharospasm-oro-mandibular dystonia, with Jankovic referring to the first two as incomplete and the latter as complete. The etiology of Meige syndrome is unknown and may be related to abnormalities in the upper brainstem and basal ganglia. It is debatable whether cases with a definite intracerebral lesion should be excluded from the diagnosis of idiopathic blepharospasm-abnormal orofacial jaw tone syndrome. In elderly patients presenting with ocular discomfort, dry eyes, shyness, and increased blinking, the possibility of early Meige syndrome should be thought of after excluding conjunctivitis and should be observed dynamically; elderly patients presenting with typical blepharospasm and/or oromandibular dystonia should be differentiated from lateral myelomeningocele, neurosis, and delayed dyskinesia due to antipsychotic drugs. The pathogenesis of Meige syndrome is unclear, and treatment is difficult.