Vitiligo is a common acquired pigmented skin disease, the symptoms of which are limited or generalized pigment loss spots on the skin. The skin damage caused by this disease directly affects the appearance of the patient and brings a serious psychological burden to the patient. As vitiligo is a difficult skin disease, a variety of treatment methods have emerged, but most of them have a long course, slow effect, patient compliance is not good, and the results are not very satisfactory. Therefore the fast way is to target the missing melanocyte replenishment, the current safe and effective method is surgical treatment autologous epidermal transplantation.
The main pathological change in vitiligo is the destruction of melanocytes in the epidermis. Autologous epidermal transplantation is a surgical method of restoring normal color to the white areas by transplanting the patient’s own normal epidermis to the white areas and obtaining melanocytes in the normal epidermis. This surgical method was first applied by Falabellaetal. in 1971.
Vitiligo autologous epidermal transplantation is a short procedure, does not require hospitalization, is less painful, has a high cure rate, and leaves no scarring afterwards. In most cases, local pigmentation starts to regenerate in about 2 weeks and continues to expand, and the pigmentation expands to the maximum in 3 to 6 months, up to double the original size. The success rate is around 90%. Autologous epidermal transplantation is suitable for patients with stable (stable white spots for at least 6 months or more than 6 months) or segmental vitiligo who have failed to respond to medication and phototherapy.
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